Speakers (Alphabetical Order)

President Lectures

Thomas M.S. Chang

Thomas M.S. Chang

[McGill University, Canada]

What is the most effective replacement for blood loss?

Hiromi Sakai

Hiromi Sakai

[Nara Medical University, Japan]

Artificial Red Cells Project in Japan

Chengmin Yang

Chengmin Yang

[Inst. Blood Transfusion, Chin. Acad. Med. Sci., China]

The exploration and discussion about the guiding principle of HBOCs research and design

Plenary Lectures

Felice D’Agnillo

[CBER, FDA, USA]

Preclinical Perspective on the Cardiovascular Responses to Hemoglobin-Based Oxygen Carriers

Koji Eto

Koji Eto

[Kyoto University, Japan]

Turning Stem Cells into Platelets

Jonathan S Jahr

Jonathan S Jahr

[Univ. of California, Los Angeles, USA]

Blood Component and Transfusion Requirements and Mortality in the Two Largest Phase III Trials of HBOCs.

Jiaxin Liu

Jiaxin Liu

[Inst. Blood Transfusion, Chin. Acad. Med. Sci., China]

Development and future of Chinese Transfusion Medicine

Masahiro Satake

Masahiro Satake

[Japanese Red Cross]

Current blood program and blood substitutes

Chao Chen

Chao Chen

[Northwest Univ., China]

Preclinical Investigation of Polymerized Porcine Hemoglobin

Keynote Lectures

Leif Büülow

Leif Bülow

[Lund University, Sweden]

Protein engineering in the design of safe and robust HBOCs

Hae Won Kim

Hae Won Kim, A. Gerson Greenburg

[Brown University, USA]

Acellular Hemoglobin-based Oxygen Carrier (HBOC)-mediated Bradycardia: Another Affair with Nitric Oxide?

Carleton Hsia

Carleton Hsia

[Synzyme, AntiRadical Therapeutics, NanoBlood, USA]

SanFlow for Unmet Medical Needs Caused by Superoxide Toxicity

Yasuo Ikeda

Yasuo Ikeda

[Waseda University, Japan]

Innovative research approach to produce a large quantity of regenerated platelets/platelet substitutes in Japan

Marcos Intaglietta

Marcos Intaglietta

[University of California, San Diego, USA]

Restoration of oxygen carrying capacity/delivery capacity in anemia

Koichi Kobayashi

Koichi Kobayashi

[Keio University, Japan]

History of Blood Substitutes Research in Japan

Jin Liu

Jin Liu

[West China Hospital, Sichuan Univ., China]

Individualized Red-cell Transfusion Strategy for Non-cardiac Surgery in Adults: a prospective, open-label, randomized clinical trial

Masaki Otagiri

Masaki Otagiri

[Sojo University, Japan]

Human Albumin Based Drug Delivery : SNO-Albumin dimer for cancer therapeutic application

Zhiguo Su

Zhiguo Su

[Chin. Acad. Sci., China]

Hemoglobin modification engineering

Shinji Takeoka

Shinji Takeoka

[Waseda University, Japan]

Evaluation of fibrinogen dodecapeptide(H12)-coated, ADP-encapsulated liposomes as hemostatic nanoparticles

(Luncheon Seminars)

Shigeyuki Kano

Shigeyuki Kano

[Res. Inst. Natl Center for Global Health & Med., Japan]

Big issues for the world malaria elimination

Midori Shima

Midori Shima

[Nara Medical University, Japan]

New therapy for hemophilia A by factor VIII mimicking bispecific antibody

Invited Lectures

Seetharama A Acharya

Seetharama A Acharya

[Dept. Med., Albert Einstein College of Medicine, USA]

Increased Oxygen Extraction from RBCs during Anemia by High O2 Affinity Hb in Plasma: Combining Supra Plasma Expansion with O2 Transfer Catalysis by Hb for Treating Anemia.

Jun Araki

Jun Araki

[Shizuoka Cancer Center Hospital, Japan]

Normothermic preservation of the rat hind limb with artificial oxygen-carrying hemoglobin vesicles and the possibility of therapeutic application

Hiroshi Azuma

Hiroshi Azuma

[Asahikawa Med. Univ., Japan]

Induction of B7-H3 positive myeloid-derived suppressor cells (MDSC) by liposomal nanoparticles

Hans Bäumler

Hans Bäumler

[Charité-Universitätsmedizin Berlin, Institute of Transfusion Medicine, Germany]

Hemoglobin submicron particles as carriers for oxygen and drugs

Olga Bockeria

Olga Bockeria

[Medical Technology Associates II, VP Clinical Development, USA]

Mitered oxygen delivery and transport to prevent ischemia and reperfusion injury of the heart

Stefano Bruno

Stefano Bruno

[University of Parma, Italy]

Different oxygen stress induced by high- and low-affinity PEGylated hemoglobin-based oxygen carriers in a Guinea pig exchange transfusion model

Pedro Cabrales

Pedro Cabrales

[Univ. of California, San Diego, USA]

PolyHb toxicity is determined by molecular weight

Surapong Chatpun

Surapong Chatpun

[Price of Songkla University, Thailand]

Characterization of hydroxypropyl, acid-thinned waxy tapioca starch based plasma expander

Limin Chen

Limin Chen

[Inst. Blood Transfusion, Chin. Acad. Med. Sci., China]

What we learned from HCV: Road leads to the control of transfusion-transmitted infectious diseases

Chris Cooper

Chris Cooper

[University of Essex, UK]

New design approaches for a recombinant haemoglobin based oxygen carrier

Allan Doctor

Allan Doctor

[KaloCyte, University of Maryland, USA]

ErythroMer: Bio-inspired Design and Performance Data for Nanofabricated Artificial Red Blood Cells

osuke Hagisawa

Kosuke Hagisawa

[National Defense Medical College, Japan]

Combination therapy using fibrinogen γ-chain peptide-coated, ADP-encapsulated liposomes and hemoglobin vesicles for trauma-induced massive hemorrhage in thrombocytopenic rabbits

Hirohisa Horinouchi

Hirohisa Horinouchi

[Saitama City Hospital, Japan]

Hemoglobin Vesicle: resuscitation fluid for hemorrhagic shock

Lihua Hu

Lihua Hu

[Huazhong Univ. Sci.&Eng., China]

Patient blood management

Yubin Huang

Yubin Huang

[Changchun Inst. Appl. Chem. CAS, China]

Design of Hemoglobin-Polymer Nano-assemblies for Oxygen Transfusion and Other Biomedical Attempts

Tatsuhiro Ishida

Tatsuhiro Ishida

[Tokushima University, Japan]

Immunological response to PEGylated liposomes: production of anti-PEG antibodies and their affection on PK of second dose

Yiping Jia

[FDA, USA]

CMC Regulatory Considerations in the Drug Development of Hemoglobin-Based Oxygen Carriers

Peter Keipert

Peter Keipert

[Keipert Corp., USA]

Pegylated HBOCs with higher oxygen affinity effectively target oxygen delivery to ischemic and/or hypoxic tissues

Manabu Kinoshita

Manabu Kinoshita

[National Defense Medical College, Japan]

Medical countermeasure using hemoglobin vesicles against trauma hemorrhagic shock

Hiroaki Kitagishi

Hiroaki Kitagishi

[Doshisha University, Japan]

Biological Roles of Endogenous Carbon Monoxide in Blood

Sompong Klaynongsruang

Sompong Klaynongsruang

[Khon Kaen University, Thailand]

Crocodile hemoglobin: Challenging and beyond

Ronald Kluger

Aizhou Wang, Ronald Kluger

[Toronto University, Canada]

Designs and Benefits of Oxygen Carriers from Site-Selectively Coupled Cross-Linked Hemoglobins

Teruyuki Komatsu

Teruyuki Komatsu

[Chuo University, Japan]

Hemoglobin-Albumin Cluster "HemoAct™" as Red Blood Cell Substitute and O2 Therapeutic Reagent

Marie Pierre Krafft

Marie Pierre Krafft

[CNRS, University of Strasbourg, France]

Advances in Fluorocarbon-Assisted Oxygen Delivery, Diagnostics and Theranostics

William R. Light

William R. Light

[VirTech Bio, USA]

VirTech Bio's progress and future plans with a large human hemoglobin polymer

Zhong Liu

Zhong Liu

[Inst. Blood Transfusion, Chin. Acad. Med. Sci., China]

20 Year Journey of blood safety in China

Feng Ma

Feng Ma

[Inst. Blood Transfusion, Chin. Acad. Med. Sci., China]

Erythroctes derived from hematopoietic stem cell-independent pathway

Judith Martini

Judith Martini

[Medical University of Innsbruck, Austria]

Bleeding management is coagulation management: The European approach of targeted coagulation therapy in massive bleeding

Toru Maruyama

Toru Maruyama

[Kumamoto University, Japan]

Albumin Fusion Protein: Next Generation of Albumin Preparation

Yumiko Matsubara

Yumiko Matsubara

[Keio Univ., Japan]

Megakaryocytes and Platelets from a Novel Source, Human Adipose-derived Mesenchymal Stem Cells

Naoto Matsuno

Naoto Matsuno

[Asahikawa Medical University, Japan]

Present status of transplant organ preservation by dynamic machine perfusion system: How important is the development of a novel organ preservation solution?

Kenichi Miharada

Kenichi Miharada

[Lund Univ., Sweden / Kumamoto Univ., Japan]

Identification of potential chemical compounds able to trigger enucleation of immortalized human erythroid cell lines

Hidenobu Ohta

Hidenobu Ohta

[Natl Center Neurol. & Psychiatry, Japan]

Hemoglobin vesicles treatment in future perinatal medicine

Andre Palmer

Andre Palmer

[The Ohio State University, USA]

Mixtures of tense and relaxed state polymerized human hemoglobin regulate oxygen affinity and tissue construct oxygenation.

Carl W. Rausch

Carl W. Rausch

[8-BioMed, Hong Kong]

A different perspective on hemoglobin solutions: The need to move beyond the mis-directed classification of "blood" substitutes

Naoaki Rikihisa

Naoaki Rikihisa

[Chiba University, Japan]

Artificial red blood cells as potential photosensitizers in laser treatment against red birthmarks

Takaaki Sato

Takaaki Sato

[Shinshu University, Japan]

Microscopic Structural Insights into Hemoglobin Vesicles (HbVs) and Closely Related Polymer and Protein solutions

Jinhai Shi

Jinhai Shi

[China Protein Drug Quality Alliance, China]

Therapy Developments for Oxygen Supply

Janos Szebeni

Janos Szebeni

[Semmelweis University, Hungary]

Liposome-encapsulated hemoglobin: Review of the progress of a synthetic red cell

Kazuaki Taguchi

Kazuaki Taguchi

[Keio University, Japan]

Carbon monoxide bound Hemoglobin-vesicles are effective in treating inflammatory disorders

Bonpei Takase

Bonpei Takase

[National Defense Medical College, Japan]

Chronic anti-arrhythmogenic effect of liposome-encapsulated hemoglobin (HbV) on the Myocardium through improving myocardial electrical remodeling and the arrhythmogenic substrate in hemorrhagic shock heart syndrome

Katsuo Terui

Katsuo Terui

[Saitama Medical University, Japan]

Critical obstetric hemorrhage:perinatal system problem in Japan and need for blood substitutes

Amy G. Tsai

Amy G. Tsai

[University of California, San Diego, USA]

Microvascular response to blood transfusion in a moderately anemic hamster model shows the importance of oxygen delivery over oxygen-carrying capacity.

Binglou Wong

Binglou Wong

[Inst. Blood Transfusion, Chin. Acad. Med. Sci., China]

From a different angle: How to make hemoglobin based oxygen carrier (HBOC) work for human application.

Rong Xia

Rong Xia

[Huashan Hospital Affiliated to Fudan Univ., China]

Basic and clinical aspects of platelet transfusion Refractoriness

Kunping Yan

Kunping Yan

[College of Life Sciences, Northwest University, China]

The study of 300% isovolemic exchange transfusion with polymerized porcine hemoglobin in rats

Zaf Zafirelis

[Hemoglobin Oxygen Therapeutics LLC, USA]

Hemopure, in the aftermath of HBOC industry's collapse following the fateful 2008 FDA/NIH workshop: What have we learned since then?

Franck Zal

Franck Zal

[Hemarina, France]

First-in-human use of a marine oxygen carrier for organ preservation: a safety and proof-of-principle study.

Hequn Zou

Hequn Zou

[The Third Affiliated Hospital of Southern Medical Univ., China]

Study on the Mechanism of Plasma Adsorption (PA) in Treating Amyotrophic Lateral Sclerosis (ALS) and Potential Pathogenesis of ALS

And More ....